Daily Archives: June 6, 2022
Analysis of Age, Race, Ethnicity, and Sex of Participants in Clinical Trials Focused on Disorders of Gut-Brain Interaction
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Further Insights Into the Impact of Bariatric Surgery on the Progression of Nonalcoholic Fatty Liver Disease
Seeberg KA, Borgeraas H, Hofsø H, et al. Gastric bypass versus sleeve gastrectomy in type 2 diabetes: effects on hepatic steatosis and fibrosis: a randomized controlled trial. Ann Intern Med 2022;175:74–83. Continue reading
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Metabolome changes with diet-induced remission in pediatric Crohn’s disease
Crohn’s Disease Exclusion Diet + Partial Enteral Nutrition (CDED+PEN) and exclusive enteral nutrition (EEN) both induce remission in pediatric Crohn’s disease (CD). CDED+PEN is better tolerated and able to sustain remission. We characterized the change… Continue reading
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Uncovering 1,058 novel human enteric DNA viruses through deep long-read third-generation sequencing and their clinical impact
Lack of viral reference genomes poses a challenge to virome study. We investigated human gut virome and its clinical implication by ultra-deep metagenomic sequencing. Continue reading
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Vonoprazan Triple and Dual Therapy for Helicobacter pylori Infection in the US and Europe: Randomized Clinical Trial
Novel, effective treatments for Helicobacter pylori infection are needed. This study evaluated the efficacy of vonoprazan, a potassium-competitive acid blocker, versus standard treatment on H. pylori eradication in the US and Europe. Continue reading
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A MULTICENTER RANDOMIZED CONTROLLED TRIAL OF SURVEILLANCE VERSUS ENDOSCOPIC THERAPY FOR BARRETT’S ESOPHAGUS WITH LOW-GRADE DYSPLASIA: THE SURVENT TRIAL STUDY RATIONALE, METHODOLOGY, INNOVATION AND IMPLICATIONS
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