Daily Archives: February 2, 2019

Early Detection of Pancreatic Cancer: Opportunities and Challenges

The vast majority of patients with pancreatic ductal adenocarcinoma (PDAC) presents with symptomatic, surgically unresectable disease. While the goal of early detection of PDAC is laudable, and likely to result in significant improvement in overall sur… Continue reading

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Fibroblasts in Pancreatic Ductal Adenocarcinoma: biological mechanisms and therapeutic targets

The desmoplastic reaction of pancreas cancer may begin as a wound healing response to the nascent neoplasm, but it soon creates an insidious shelter that can sustain the growing tumor and rebuff therapy. Among the many cell types subverted by transform… Continue reading

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