{"id":68,"date":"2015-06-29T20:00:00","date_gmt":"2015-06-30T01:00:00","guid":{"rendered":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/?guid=9c3f091332da6540b829a0eabe1944ac"},"modified":"2015-06-29T20:00:00","modified_gmt":"2015-06-30T01:00:00","slug":"reply","status":"publish","type":"post","link":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/2015\/06\/reply\/","title":{"rendered":"Reply"},"content":{"rendered":"

Many thanks to Dong et\u00a0al for their correspondence regarding our phase II randomized, controlled trial (NCT00550862) of obeticholic acid (OCA) in primary biliary cirrhosis (PBC).1 Notably, we were able to demonstrate biochemical efficacy of OCA in patients with PBC and inadequate response to ursodeoxycholic acid\u00a0(UDCA), supporting the scientific rationale for using\u00a0this semisynthetic analog of the primary bile acid chenodeoxycholic acid, which selectively activates the nuclear hormone receptor farnesoid X receptor.<\/p>\n","protected":false},"excerpt":{"rendered":"

Many thanks to Dong et\u00a0al for their correspondence regarding our phase II randomized, controlled trial (NCT00550862) of obeticholic acid (OCA) in primary biliary cirrhosis (PBC).1 Notably, we were able to demonstrate biochemical efficacy of OCA in pat… Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":3901,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-68","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/posts\/68","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/users\/3901"}],"replies":[{"embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/comments?post=68"}],"version-history":[{"count":3,"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/posts\/68\/revisions"}],"predecessor-version":[{"id":771,"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/posts\/68\/revisions\/771"}],"wp:attachment":[{"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/media?parent=68"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/categories?post=68"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/tags?post=68"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}