{"id":11327,"date":"2017-04-03T01:00:00","date_gmt":"2017-04-03T06:00:00","guid":{"rendered":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/?guid=08a138d5776915d742f5d258bab48cdc"},"modified":"2017-04-03T23:00:00","modified_gmt":"2017-04-04T04:00:00","slug":"reply-61","status":"publish","type":"post","link":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/2017\/04\/reply-61\/","title":{"rendered":"Reply"},"content":{"rendered":"<p>Dai et\u00a0al provided comments on the use of the nonsystemic antibiotic rifaximin for diarrhea-predominant irritable bowel syndrome (IBS-D) and data from the TARGET 3 repeat treatment trial of rifaximin for adults with\u00a0IBS-D.1 Specifically, concerns were voiced regarding the\u00a0percentage improvement over placebo reported in the TARGET 3 trial.1 However, it is important to note that TARGET 3 was not a primary efficacy trial. Two randomized, double-blind, placebo-controlled, phase III trials (TARGET 1 and 2) previously demonstrated the efficacy of rifaximin over placebo.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dai et\u00a0al provided comments on the use of the nonsystemic antibiotic rifaximin for diarrhea-predominant irritable bowel syndrome (IBS-D) and data from the TARGET 3 repeat treatment trial of rifaximin for adults with\u00a0IBS-D.1 Specifically, concerns wer&#8230; <a href=\"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/2017\/04\/reply-61\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":5910,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-11327","post","type-post","status-publish","format-standard","hentry","category-news"],"_links":{"self":[{"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/posts\/11327","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/users\/5910"}],"replies":[{"embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/comments?post=11327"}],"version-history":[{"count":24,"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/posts\/11327\/revisions"}],"predecessor-version":[{"id":12370,"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/posts\/11327\/revisions\/12370"}],"wp:attachment":[{"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/media?parent=11327"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/categories?post=11327"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/richardpeek\/wp-json\/wp\/v2\/tags?post=11327"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}