STAT3 Mediated Remodeling of the Tumor Microenvironment Results in Enhanced Tumor Drug Delivery in a Mouse Model of Pancreatic Cancer

Posted on August 6, 2015 by Nagaraj S. Nagathihalli, Jason A. Castellanos, Chanjuan Shi, Yugandhar Beesetty, Michelle L. Reyzer, Richard Caprioli, Xi Chen, Alex J. Walsh, Melissa C. Skala, Harold L. Moses, Nipun B. Merchant

STAT3 inhibition combined with gemcitabine remodels the tumor stroma to enhance tumor drug delivery and improve survival in a genetic mouse model of pancreatic cancer.

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