Interleukin 6 Increases Production of Cytokines by Colonic Innate Lymphoid Cells in Mice and Patients With Chronic Intestinal Inflammation

Posted on April 24, 2015 by Nick Powell, Jonathan W. Lo, Paolo Biancheri, Anna Vossenkämper, Eirini Pantazi, Alan W. Walker, Emilie Stolarczyk, Francesca Ammoscato, Rimma Goldberg, Paul Scott, James B. Canavan, Esperanza Perucha, Natividad Garrido-Mesa, Peter M. Irving, Jeremy

Innate lymphoid cells (ILCs) are a heterogeneous group of mucosal inflammatory cells that participate in chronic intestinal inflammation. We investigated the role of interleukin 6 (IL6) in inducing activation of ILCs in mice and in human beings with chronic intestinal inflammation.

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