Monthly Archives: February 2018
Opioid use increases risk of serious infections: study
Opioid users have a significantly increased risk of infections severe enough to require treatment at the hospital, such as pneumonia and meningitis, as compared to people who don’t use opioids. Continue reading
Uniform and scrub sale at Children’s Hospital today and tomorrow
Ohde remembered as consummate teacher, researcher
Ralph Ohde, PhD, professor emeritus of Hearing and Speech Sciences at the Vanderbilt Bill Wilkerson Center, died Jan. 8. He was 73. Dr. Ohde taught speech science at Vanderbilt for more than 30 years, including graduate level courses in articulation di… Continue reading
Children’s Hospital to launch new website design tomorrow
The new site was built with mobile users in mind. More than half of visitors view the site on a mobile device. To that end, content has been streamlined with an emphasis on fewer pages and more scrolling. Continue reading
Early Career Faculty Seminar on the “imposter syndrome” to be April 23
Less is more: A minimalist approach to endoscopy
A substantial literature documents inappropriate usage of gastrointestinal endoscopy in a variety of clinical settings. Overusage of endoscopy appears to be common, and 30% or more of procedures performed in some clinical settings have questionable ind… Continue reading
Functional Bowel Disorders Gastroenterology’s 75th anniversary
Articles appearing in Gastroenterology have played an integral role in the evolution of our understanding of Functional Bowel Disorders (FBD), including Irritable Bowel Syndrome (IBS), beginning with the prescient contributions of Almy and Tulin in 194… Continue reading
Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients with Crohn’s Disease
A subset of pediatric Crohn’s Disease patients exhibit damaging mutations in core NADPH oxidase genes which are associated with reduced neutrophil reactive oxygen species production and a more aggressive clinical course. Continue reading
Alterations in Intestinal Microbiota Lead to Production of Interleukin 17 by Intrahepatic γδ T-cell Receptor-positive Cells and Pathogenesis of Cholestatic Liver Disease
Variants at the ATP binding cassette subfamily B member 4 gene (ABCB4 or MDR2) locus, which encodes a biliary transport protein, are associated with a spectrum of cholestatic liver diseases. Exacerbation of liver disease has been linked to increased he… Continue reading
HCV Genotype 6a Escape from and Resistance to Velpatasvir, Pibrentasvir, and Sofosbuvir in Robust Infectious Cell Culture Models
Chronic liver diseases caused by hepatitis C virus (HCV) genotype 6 are prevalent in Asia, and millions of people require treatment with direct-acting antiviral regimens, such as NS5A inhibitor velpatasvir combined with the NS5B polymerase inhibitor so… Continue reading