Monthly Archives: February 2018
Advances and challenges in endoscopic training
One of the challenges of the current era is ensuring that endoscopic training is accomplished effectively in the face of multiple competing demands. As healthcare delivery evolves, with rising patient complexity and increasing productivity requirements… Continue reading
P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-promoting Myofibroblasts
Hepatic stellate cells (HSCs) contribute to desmoplasia and stiffness of liver metastases by differentiating into matrix-producing myofibroblasts. We investigated whether stiffness due to the presence of tumors increases activation of HSCs into myofibr… Continue reading
Endoscopic Myotomy for Foregut Motility Disorders
Peroral endoscopic myotomy (POEM) is an advanced endoscopic procedure classically performed for the treatment of achalasia. The procedure is based on principles of submucosal endoscopy and is comprised of a mucosal incision, submucosal tunneling, myoto… Continue reading
Increased Expression of the Long Non-coding RNA LINC01503, Regulated by TP63, in Squamous Cell Carcinoma and Effects on Oncogenic Activities of Cancer Cell Lines
Long non-coding RNAs (lncRNAs) are expressed in tissue-specific pattern, but it is not clear how these are regulated. We aimed to identify squamous cell carcinoma (SCC)-specific lncRNAs and investigate mechanisms that control their expression and funct… Continue reading
Advances in CRC prevention: screening and surveillance
Colorectal cancer (CRC) is amongst the most commonly diagnosed cancers and causes of death from cancer across the world. CRC can, however, be detected in asymptomatic patients at a curable stage, and several studies have shown lower mortality among pat… Continue reading
Endoscopic Management of Transmural Defects (Leaks/Perforations/Fistulae)
Transmural defects of the gastrointestinal tract can be classified into three distinct entities that include leaks, perforations, and fistulae. Each arise from different mechanisms and are managed accordingly. Leaks occur most often following surgery, … Continue reading
Chinese New Year is tomorrow; Vanderbilt celebration is Feb. 18
There will be catered Chinese food, red envelopes, cultural trivia, karaoke, games, a Lion Dance performance from the Chinese Arts Alliance of Nashville, and plentiful opportunities to meet new people. Continue reading
Love is all around on babies’ first Valentine’s Day
In recognition of Heart Month, VUMC’s tiniest sweethearts celebrated Valentine’s Day by creating a special gift for their loved ones. Babies in Vanderbilt’s Newborn Nursery and Neonatal Intensive Care Unit had their feet painted and placed on a onesie … Continue reading