{"id":2802,"date":"2023-08-01T13:58:30","date_gmt":"2023-08-01T18:58:30","guid":{"rendered":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/?page_id=2802"},"modified":"2023-08-01T13:59:14","modified_gmt":"2023-08-01T18:59:14","slug":"early-zebrafish-development","status":"publish","type":"page","link":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/early-zebrafish-development\/","title":{"rendered":"Early Zebrafish Development"},"content":{"rendered":"<h4>Gestation and Overview of Development<\/h4>\n<p>In comparison to other vertebrates, especially humans, zebrafish development occurs rather rapidly where the majority of embryogenesis occurs by\u00a03 dpf \/72 hpf.\u00a0 You can watch a very cool video\u00a0that shows the entire process of zebrafish embryogenesis from the 1 cell stage &#8211;\u00a0to hatching at this link (<a href=\"https:\/\/youtu.be\/EeHiA98yUa4\" target=\"_blank\">Zebrafish Development from egg to embryo<\/a>).<\/p>\n<h4>Early Embryogenesis:<\/h4>\n<p>Zebrafish eggs are <a href=\"https:\/\/en.wikipedia.org\/wiki\/Telolecithal\" target=\"_blank\">telolecithal<\/a>, which means that a majority of the egg is made up of yolk. Since cleavage can only occur in yolk free zone, this means that cell divisions are not able to completely divide the egg (meroblastic). The first few cell divisions follow a reproducible pattern occurring around every 15 mins. Gastrulation occurs at around ~5.25 hours (50% epiboly) and leads to the formation of all three germ layers (mesoderm, endoderm, and ectoderm) (Gilbert 2014).<\/p>\n<p>&nbsp;<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2803 aligncenter\" src=\"https:\/\/cdn-dev.vanderbilt.edu\/t2-my-dev\/wp-content\/uploads\/sites\/2855\/2023\/08\/zebrafish-development--300x250.jpg\" alt=\"zebrafish development\" width=\"454\" height=\"378\" srcset=\"https:\/\/cdn-dev.vanderbilt.edu\/t2-my-dev\/wp-content\/uploads\/sites\/2855\/2023\/08\/zebrafish-development--300x250.jpg 300w, https:\/\/cdn-dev.vanderbilt.edu\/t2-my-dev\/wp-content\/uploads\/sites\/2855\/2023\/08\/zebrafish-development-.jpg 696w\" sizes=\"auto, (max-width: 454px) 100vw, 454px\" \/><\/p>\n<p style=\"text-align: center\"><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/B9780128124314000452\" target=\"_blank\">Chapter 45 &#8211; Zebrafish as a Model to Understand Vertebrate Development<\/a><\/p>\n<p style=\"text-align: left\">\n","protected":false},"excerpt":{"rendered":"<p>Gestation and Overview of Development In comparison to other vertebrates, especially humans, zebrafish development occurs rather rapidly where the majority of embryogenesis occurs by\u00a03 dpf \/72 hpf.\u00a0 You can watch a very cool video\u00a0that shows the entire process of zebrafish embryogenesis from the 1 cell stage &#8211;\u00a0to hatching at this link (Zebrafish Development from egg&#8230;<\/p>\n","protected":false},"author":9901,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"tags":[],"class_list":["post-2802","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/pages\/2802","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/users\/9901"}],"replies":[{"embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/comments?post=2802"}],"version-history":[{"count":2,"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/pages\/2802\/revisions"}],"predecessor-version":[{"id":2805,"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/pages\/2802\/revisions\/2805"}],"wp:attachment":[{"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/media?parent=2802"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/tags?post=2802"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}