{"id":2247,"date":"2019-08-01T18:21:24","date_gmt":"2019-08-01T23:21:24","guid":{"rendered":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/?page_id=2247"},"modified":"2019-08-02T09:08:14","modified_gmt":"2019-08-02T14:08:14","slug":"cdh-severity-classifications","status":"publish","type":"page","link":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/home\/2019-projects\/frog-muscle\/disease-highlight-congenital-diaphragmatic-hernia\/cdh-severity-classifications\/","title":{"rendered":"CDH Severity Classifications"},"content":{"rendered":"
\"Cartoon<\/a>
Cartoon depiction of different CDH severity classes. The diaphragm is represented as the center pink region with hernias of varying size as black shaded areas.<\/figcaption><\/figure>\n

 <\/p>\n

Severity<\/strong><\/p>\n

CDH is classified (in order of increasing severity) as type A, B, C, or D<\/strong>. Generally, diseases of type A are quite mild and the patient’s quality of life is minimally affected. Type B and C\u00a0are intermediate\u00a0in severity, while type D is often fatal and requires the most extensive intervention. Physicians also often report a lung-to-head ratio (LHR)<\/strong><\/a>. This is a numeric estimate of the size of the fetal lungs based on what is visible, with LHR>1.0 often foreshadowing favorable clinical outcomes.<\/p>\n

Below, note data<\/strong> on persons diagnosed with CDH provided by Vanderbilt Children’s Hospital<\/strong><\/a>, compared with the University of Texas CDH Registry<\/strong><\/a>. This registry provides data reported by over 50 fetal care centers nationwide. Interestingly, Vanderbilt\u00a0Children’s Hospital\u00a0and the CDH Registry report stark differences in the percentage of patients surviving defect D*.<\/strong><\/span> This may\u00a0reflect\u00a0diagnostic inconsistencies\u00a0across different centers.<\/p>\n

 <\/p>\n

\"Reported
Reported numbers by Vanderbilt Children’s Hospital compared to the CDH registry.<\/figcaption><\/figure>\n

*These discrepancies\u00a0warrant more precise classification standards for CDH across different care centers.<\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"

  Severity CDH is classified (in order of increasing severity) as type A, B, C, or D. Generally, diseases of type A are quite mild and the patient’s quality of life is minimally affected. Type B and C\u00a0are intermediate\u00a0in severity, while type D is often fatal and requires the most extensive intervention. Physicians also often…<\/p>\n","protected":false},"author":8390,"featured_media":0,"parent":2042,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"tags":[],"class_list":["post-2247","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/pages\/2247","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/users\/8390"}],"replies":[{"embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/comments?post=2247"}],"version-history":[{"count":5,"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/pages\/2247\/revisions"}],"predecessor-version":[{"id":2304,"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/pages\/2247\/revisions\/2304"}],"up":[{"embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/pages\/2042"}],"wp:attachment":[{"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/media?parent=2247"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/pdbbootcamp\/wp-json\/wp\/v2\/tags?post=2247"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}