{"id":58,"date":"2019-07-05T19:17:31","date_gmt":"2019-07-06T00:17:31","guid":{"rendered":"https:\/\/my.dev.vanderbilt.edu\/knapiklab\/?page_id=58"},"modified":"2019-07-16T14:31:30","modified_gmt":"2019-07-16T19:31:30","slug":"publications","status":"publish","type":"page","link":"https:\/\/my.dev.vanderbilt.edu\/knapiklab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

2019<\/h2>\n

GRIK5 Genetically Regulated Expression Associated with Eye and Vascular Phenomes: Discovery through Iteration among Biobanks, Electronic Health Records, and Zebrafish.<\/a><\/p>\n

\n

Unlu G<\/strong>, Gamazon ER, Qi X<\/strong>, Levic DS<\/strong>, Bastarache L, Denny JC, Roden DM, Mayzus I, Breyer M, Zhong X, Konkashbaev AI, Rzhetsky A,\u00a0Knapik EW<\/b>, Cox NJ.<\/p>\n

Am J Hum Genet<\/span>. 2019 Mar 7;104(3):503-519. doi: 10.1016\/j.ajhg.2019.01.017. Epub 2019 Feb 28. PMID: 30827500<\/p>\n

2018<\/h2>\n

Dynamic Glycosylation Governs the Vertebrate COPII Protein Trafficking Pathway.<\/a><\/p>\n

\n

Cox NJ, Unlu G<\/strong>, Bisnett BJ, Meister TR, Condon BM, Luo PM, Smith TJ, Hanna M, Chhetri A, Soderblom EJ, Audhya A,\u00a0Knapik EW<\/b>, Boyce M.<\/p>\n

Biochemistry<\/span>. 2018 Jan 9;57(1):91-107. doi: 10.1021\/acs.biochem.7b00870. Epub 2017 Dec 15. PMID: 29161034<\/p>\n<\/div>\n<\/div>\n

2017<\/h2>\n

Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes.<\/a><\/p>\n

\n

Hockman D, Burns AJ, Schlosser G, Gates KP, Jevans B, Mongera A, Fisher S, Unlu G<\/strong>,\u00a0Knapik EW<\/b>, Kaufman CK, Mosimann C, Zon LI, Lancman JJ, Dong PDS, Lickert H, Tucker AS, Baker CV.<\/p>\n

Elife<\/span>. 2017 Apr 7;6. pii: e21231. doi: 10.7554\/eLife.21231. PMID: 28387645<\/p>\n<\/div>\n

Zebrafish Developmental Models of Skeletal Diseases.<\/a><\/p>\n

\n

Luderman LN<\/strong>, Unlu G<\/strong>,\u00a0Knapik EW<\/b>.<\/p>\n

Curr Top Dev Biol<\/span>. 2017;124:81-124. doi: 10.1016\/bs.ctdb.2016.11.004. Epub 2017 Jan 4. Review. PMID: 28335865<\/p>\n<\/div>\n

2015<\/h2>\n

Animal model of Sar1b deficiency presents lipid absorption deficits similar to Anderson disease.<\/a><\/p>\n

\n

Levic DS<\/strong>, Minkel JR, Wang WD<\/strong>, Rybski WM<\/strong>, Melville DB<\/strong>,\u00a0Knapik EW<\/b>.<\/p>\n

J Mol Med (Berl)<\/span>. 2015 Feb;93(2):165-76. doi: 10.1007\/s00109-014-1247-x. Epub 2015 Jan 7. PMID: 25559265<\/p>\n

2014<\/h2>\n

Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway.<\/a><\/p>\n

\n

Tanwar V, Bylund JB, Hu J, Yan J, Walthall JM, Mukherjee A, Heaton WH, Wang WD<\/strong>, Potet F, Rai M, Kupershmidt S,\u00a0Knapik EW<\/b>, Hatzopoulos AK.<\/p>\n

Stem Cells<\/span>. 2014\u00a0 Jul;32(7):1774-88. doi: 10.1002\/stem.1703. PMID: 24648383<\/p>\n

The nuclear pore complex function of Sec13 protein is required for cell survival during retinal development.<\/a><\/p>\n

\n

Niu X, Hong J, Zheng X, Melville DB<\/strong>,\u00a0Knapik EW<\/b>, Meng A, Peng J.<\/p>\n

J Biol Chem<\/span>. 2014 Apr 25;289(17):11971-85. doi: 10.1074\/jbc.M114.547190. Epub 2014 Mar 13. PMID: 24627485<\/p>\n

In vivo cell biology in zebrafish – providing insights into vertebrate development and disease.<\/a><\/p>\n

\n

Vacaru AM, Unlu G<\/strong>, Spitzner M, Mione M,\u00a0Knapik EW<\/b>, Sadler KC.<\/p>\n

J Cell Sci<\/span>. 2014 Feb 1;127(Pt 3):485-95. doi: 10.1242\/jcs.140194. Review. PMID: 24481493<\/p>\n<\/div>\n<\/div>\n<\/div>\n

Trafficking mechanisms of extracellular matrix macromolecules: insights from vertebrate development and human diseases.<\/a><\/p>\n

\n

Unlu G<\/strong>, Levic DS<\/strong>, Melville DB<\/strong>,\u00a0Knapik EW<\/b>.<\/p>\n

Int J Biochem Cell Biol<\/span>. 2014 Feb;47:57-67. doi: 10.1016\/j.biocel.2013.11.005. Epub 2013 Dec 9. Review. PMID: 24333299<\/p>\n

The NADH oxidase ENOX1, a critical mediator of endothelial cell radiosensitization, is crucial for vascular development.<\/a><\/p>\n

\n

Venkateswaran A, Sekhar KR, Levic DS<\/strong>, Melville DB<\/strong>, Clark TA, Rybski WM<\/strong>, Walsh AJ, Skala MC, Crooks PA,\u00a0Knapik EW<\/b>, Freeman ML.<\/p>\n

Cancer Res<\/span>. 2014 Jan 1;74(1):38-43. doi: 10.1158\/0008-5472.CAN-13-1981. Epub 2013 Nov 18. PMID: 24247717<\/p>\n

2013<\/h2>\n

An exclusively mesodermal origin of fin mesenchyme demonstrates that zebrafish trunk neural crest does not generate ectomesenchyme.<\/a><\/p>\n

\n

Lee RT,\u00a0Knapik EW<\/b>, Thiery JP, Carney TJ.<\/p>\n

Development<\/span>. 2013 Jul;140(14):2923-32. doi: 10.1242\/dev.093534. Epub 2013 Jun 5. PMID: 23739134<\/p>\n

Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm.<\/a><\/p>\n

\n
\n

M\u00fcller II<\/strong>, Melville DB<\/strong>, Tanwar V, Rybski WM<\/strong>, Mukherjee A, Shoemaker MB, Wang WD<\/strong>, Schoenhard JA, Roden DM, Darbar D,\u00a0Knapik EW<\/b>, Hatzopoulos AK.<\/p>\n

Dis Model Mech<\/span>. 2013 Mar;6(2):332-41. doi: 10.1242\/dmm.010488. Epub 2012 Dec 7. PMID: 23223679<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

2011<\/h2>\n
\n

An SNP-Based Linkage Map for Zebrafish Reveals Sex Determination Loci.<\/a><\/p>\n

\n

Bradley KM, Breyer JP, Melville DB<\/strong>, Broman KW,\u00a0Knapik EW<\/b>, Smith JR.<\/p>\n

G3 (Bethesda)<\/span>. 2011 Jun 1;1(1):3-9. PMID: 21949597<\/p>\n

Mutations in fam20b and xylt1 reveal that cartilage matrix controls timing of endochondral ossification by inhibiting chondrocyte maturation.<\/a><\/p>\n

\n

Eames BF, Yan YL, Swartz ME, Levic DS<\/strong>,\u00a0Knapik EW<\/b>, Postlethwait JH, Kimmel CB.<\/p>\n

PLoS Genet<\/span>. 2011 Aug;7(8):e1002246. doi: 10.1371\/journal.pgen.1002246. Epub 2011 Aug 25. PMID: 21901110<\/p>\n

The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis.<\/a><\/p>\n

\n

Melville DB<\/strong>, Montero-Balaguer M<\/strong>, Levic DS<\/strong>, Bradley K, Smith JR, Hatzopoulos AK,\u00a0Knapik EW<\/b>.<\/p>\n

Dis Model Mech<\/span>. 2011 Nov;4(6):763-76. doi: 10.1242\/dmm.007625. Epub 2011 Jul 4. PMID: 21729877<\/p>\n

Tumor suppressor Lzap regulates cell cycle progression, doming, and zebrafish epiboly.<\/a><\/p>\n

\n

Liu D, Wang WD<\/strong>, Melville DB<\/strong>, Cha YI, Yin Z, Issaeva N,\u00a0Knapik EW<\/b>, Yarbrough WG.<\/p>\n

Dev Dyn<\/span>. 2011 Jun;240(6):1613-25. doi: 10.1002\/dvdy.22644. Epub 2011 Apr 26. PMID: 21523853<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n

Traffic jams in fish bones: ER-to-Golgi protein transport during zebrafish development.<\/a><\/p>\n

\n

Melville DB<\/strong>,\u00a0Knapik EW<\/b>.<\/p>\n

Cell Adh Migr<\/span>. 2011 Mar-Apr;5(2):114-8. Epub 2011 Mar 1. Review. PMID: 21178403<\/p>\n<\/div>\n

2010<\/h2>\n

Sec24D-dependent transport of extracellular matrix proteins is required for zebrafish skeletal morphogenesis.<\/a><\/p>\n

\n

Sarmah S<\/strong>, Barrallo-Gimeno A<\/strong>, Melville DB<\/strong>, Topczewski J, Solnica-Krezel L,\u00a0Knapik EW<\/b>.<\/p>\n

PLoS One<\/span>. 2010 Apr 28;5(4):e10367. doi: 10.1371\/journal.pone.0010367. PMID: 20442775<\/p>\n<\/div>\n<\/div>\n

2009<\/h2>\n

A selective glial barrier at motor axon exit points prevents oligodendrocyte migration from the spinal cord.<\/a><\/p>\n

\n

Kucenas S, Wang WD<\/strong>,\u00a0Knapik EW<\/b>, Appel B.<\/p>\n

J Neurosci<\/span>. 2009 Dec 2;29(48):15187-94. doi: 10.1523\/JNEUROSCI.4193-09.2009. PMID: 19955371<\/p>\n<\/div>\n

2008<\/h2>\n

Goodpasture antigen-binding protein and its spliced variant, ceramide transfer protein, have different functions in the modulation of apoptosis during zebrafish development.<\/a><\/p>\n

\n

Granero-Molt\u00f3 F, Sarmah S<\/strong>, O’Rear L, Spagnoli A, Abrahamson D, Saus J, Hudson BG,\u00a0Knapik EW<\/b>.<\/p>\n

J Biol Chem<\/span>. 2008 Jul 18;283(29):20495-504. doi: 10.1074\/jbc.M801806200. Epub 2008 Apr 18. PMID: 18424781<\/p>\n<\/div>\n

2007<\/h2>\n

A major zebrafish polymorphism resource for genetic mapping.<\/a><\/p>\n

\n

Bradley KM, Elmore JB, Breyer JP, Yaspan BL, Jessen JR,\u00a0Knapik EW<\/b>, Smith JR.<\/p>\n

Genome Biol<\/span>. 2007;8(4):R55. PMID: 17428331<\/p>\n<\/div>\n

2006<\/h2>\n

The mother superior mutation ablates foxd3 activity in neural crest progenitor cells and depletes neural crest derivatives in zebrafish.<\/a><\/p>\n

\n

Montero-Balaguer M<\/strong>, Lang MR<\/strong>, Sachdev SW, Knappmeyer C, Stewart RA, De La Guardia A, Hatzopoulos AK,\u00a0Knapik EW<\/b>.<\/p>\n

Dev Dyn<\/span>. 2006 Dec;235(12):3199-212. PMID: 17013879<\/p>\n

Secretory COPII coat component Sec23a is essential for craniofacial chondrocyte maturation.<\/a><\/p>\n

\n

Lang MR<\/strong>, Lapierre LA, Frotscher M, Goldenring JR,\u00a0Knapik EW<\/b>.<\/p>\n

Nat Genet<\/span>. 2006 Oct;38(10):1198-203. Epub 2006 Sep 17. PMID: 16980978<\/p>\n

Expression of the protein related to Dan and Cerberus gene–prdc–During eye, pharyngeal arch, somite, and swim bladder development in zebrafish.<\/a><\/p>\n

\n

M\u00fcller II<\/strong>,\u00a0Knapik EW<\/b>, Hatzopoulos AK.<\/p>\n

Dev Dyn<\/span>. 2006 Oct;235(10):2881-8. PMID: 16921498<\/p>\n<\/div>\n<\/div>\n<\/div>\n

2004<\/h2>\n

Neural crest survival and differentiation in zebrafish depends on mont blanc\/tfap2a gene function.<\/a><\/p>\n

\n

Barrallo-Gimeno A<\/strong>, Holzschuh J, Driever W,\u00a0Knapik EW<\/b>.<\/p>\n

Development<\/span>. 2004 Apr;131(7):1463-77. Epub 2004 Feb 25. PMID: 14985255<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

2019 GRIK5 Genetically Regulated Expression Associated with Eye and Vascular Phenomes: Discovery through Iteration among Biobanks, Electronic Health Records, and Zebrafish. Unlu G, Gamazon ER, Qi X, Levic DS, Bastarache L, Denny JC, Roden DM, Mayzus I, Breyer M, Zhong X, Konkashbaev AI, Rzhetsky A,\u00a0Knapik EW, Cox NJ. Am J Hum Genet. 2019 Mar 7;104(3):503-519….<\/p>\n","protected":false},"author":7593,"featured_media":0,"parent":0,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"tags":[],"class_list":["post-58","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/my.dev.vanderbilt.edu\/knapiklab\/wp-json\/wp\/v2\/pages\/58","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/my.dev.vanderbilt.edu\/knapiklab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/my.dev.vanderbilt.edu\/knapiklab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/knapiklab\/wp-json\/wp\/v2\/users\/7593"}],"replies":[{"embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/knapiklab\/wp-json\/wp\/v2\/comments?post=58"}],"version-history":[{"count":14,"href":"https:\/\/my.dev.vanderbilt.edu\/knapiklab\/wp-json\/wp\/v2\/pages\/58\/revisions"}],"predecessor-version":[{"id":82,"href":"https:\/\/my.dev.vanderbilt.edu\/knapiklab\/wp-json\/wp\/v2\/pages\/58\/revisions\/82"}],"wp:attachment":[{"href":"https:\/\/my.dev.vanderbilt.edu\/knapiklab\/wp-json\/wp\/v2\/media?parent=58"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/knapiklab\/wp-json\/wp\/v2\/tags?post=58"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}