{"id":3,"date":"2015-01-16T22:50:30","date_gmt":"2015-01-16T22:50:30","guid":{"rendered":"https:\/\/my.dev.vanderbilt.edu\/ericgamazon\/homepage\/"},"modified":"2025-01-02T09:58:48","modified_gmt":"2025-01-02T14:58:48","slug":"homepage","status":"publish","type":"page","link":"https:\/\/my.dev.vanderbilt.edu\/ericgamazon\/","title":{"rendered":"Home Page"},"content":{"rendered":"<p id=\"h.p_9-Hgo8lu1eFg\" class=\"zfr3Q\">We develop and apply genomic and computational methods to investigate the genetic architecture of complex traits, including disease risk and drug response. We are interested in what can be learned from DNA sequence and multi-omics data about disease mechanism, therapeutic intervention, molecular evolution, and genome <a href=\"https:\/\/doi.org\/10.1038\/s41588-024-01827-2\"><strong>function<\/strong><\/a>. An ongoing project involves understanding <a href=\"https:\/\/www.nature.com\/articles\/s41588-018-0154-4.pdf\"><strong>gene regulation<\/strong><\/a> across tissues and cell types to gain insights into disease mechanisms and therapeutic targets. We utilize large-scale DNA biobank data linked to electronic health records, along with <a href=\"https:\/\/www.nature.com\/articles\/s41588-020-0706-2.pdf\"><strong>data science and computation<\/strong><\/a>, to identify genes involved in human health and disease in <a href=\"https:\/\/www.cell.com\/cell-genomics\/pdfExtended\/S2666-979X(22)00125-2\"><strong>diverse populations<\/strong><\/a>, to discover novel biomarkers, and to enable a comprehensive systems view of the disease phenome. Here is a short description of <strong><a href=\"https:\/\/my.dev.vanderbilt.edu\/ericgamazon\/research\/\">research interests<\/a><\/strong>.<\/p>\n<hr \/>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-1056 size-full alignleft\" src=\"https:\/\/cdn-dev.vanderbilt.edu\/t2-my-dev\/wp-content\/uploads\/sites\/1706\/2015\/01\/gamazon-eric_hs.jpg\" width=\"170\" height=\"170\" srcset=\"https:\/\/cdn-dev.vanderbilt.edu\/t2-my-dev\/wp-content\/uploads\/sites\/1706\/2015\/01\/gamazon-eric_hs.jpg 170w, https:\/\/cdn-dev.vanderbilt.edu\/t2-my-dev\/wp-content\/uploads\/sites\/1706\/2015\/01\/gamazon-eric_hs-150x150.jpg 150w\" sizes=\"auto, (max-width: 170px) 100vw, 170px\" \/>Dr. Eric R. Gamazon is broadly interested in <a href=\"https:\/\/news.vumc.org\/2020\/10\/22\/new-tool-genetic-mechanisms-disease\/\" target=\"_blank\">genomics, computational biology, machine learning, and genomic medicine<\/a> and leads the Functional Genomics &amp; Precision Medicine lab. He is a tenured faculty member in the Vanderbilt University School of Medicine. <span class=\"C9DxTc \">He has <\/span><span class=\"C9DxTc \">participated in the <\/span><a class=\"XqQF9c\" href=\"https:\/\/news.vumc.org\/2020\/10\/22\/new-tool-genetic-mechanisms-disease\/\" target=\"_blank\"><span class=\"C9DxTc aw5Odc \">GTEx Consortium<\/span><\/a><span class=\"C9DxTc \">, the <\/span><a class=\"XqQF9c\" href=\"https:\/\/news.vumc.org\/2022\/12\/08\/framework-multiancestry-genomic-studies\/\" target=\"_blank\"><span class=\"C9DxTc aw5Odc \">Global Biobank Meta-analysis Initiative<\/span><\/a><span class=\"C9DxTc \">, the <\/span><a class=\"XqQF9c\" href=\"https:\/\/www.vumc.org\/potocsnak-center\/person\/eric-gamazon\" target=\"_blank\"><span class=\"C9DxTc aw5Odc \">Potocsnak Center for Undiagnosed and Rare Disorders<\/span><\/a><span class=\"C9DxTc \">, and a number of <\/span><a class=\"XqQF9c\" href=\"https:\/\/news.vumc.org\/2021\/10\/21\/genetic-variants-protein-expression-disease-connections\/\" target=\"_blank\"><span class=\"C9DxTc aw5Odc \">omics initiatives<\/span><\/a><span class=\"C9DxTc \">.<\/span><\/p>\n<p class=\"zfr3Q CDt4Ke \" dir=\"ltr\"><span class=\"C9DxTc \">The lab is an interdisciplinary hybrid environment with expertise in computational genomics and molecular biology. The lab has been the <strong>research training ground<\/strong> for a Barry Goldwater Scholar, a <\/span><span class=\"C9DxTc \">Fulbright Scholar, <\/span><span class=\"C9DxTc \">a NARSAD Young Investigator Grant recipient, and a Ruth L. Kirschstein Individual Predoctoral Fellow.\u00a0<\/span><\/p>\n<p class=\"zfr3Q\">Dr. Gamazon is a recipient of the inaugural <a href=\"https:\/\/news.vumc.org\/2019\/09\/19\/gamazon-nih-genomic-innovator-award\/\" target=\"_blank\">Genomic Innovator Award<\/a> from the National Institutes of Health (NIH). Here is a list of select <strong><a title=\"My Publications\" href=\"https:\/\/my.dev.vanderbilt.edu\/ericgamazon\/publications\/\" target=\"_blank\">publications<\/a><\/strong> and the latest <strong><a href=\"https:\/\/my.dev.vanderbilt.edu\/ericgamazon\/news\/\">news<\/a><\/strong>.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-645 alignright\" src=\"https:\/\/cdn-dev.vanderbilt.edu\/t2-my-dev\/wp-content\/uploads\/sites\/1706\/2015\/01\/5982e673bbddbd2e59168944-300x114.jpg\" alt=\"5982e673bbddbd2e59168944\" width=\"292\" height=\"111\" srcset=\"https:\/\/cdn-dev.vanderbilt.edu\/t2-my-dev\/wp-content\/uploads\/sites\/1706\/2015\/01\/5982e673bbddbd2e59168944-300x114.jpg 300w, https:\/\/cdn-dev.vanderbilt.edu\/t2-my-dev\/wp-content\/uploads\/sites\/1706\/2015\/01\/5982e673bbddbd2e59168944.jpg 350w\" sizes=\"auto, (max-width: 292px) 100vw, 292px\" \/>He is now a Life Member (2019 &#8212; present) of Clare Hall, <a class=\"dhtgD aw5Odc\" href=\"https:\/\/www.cam.ac.uk\/\" target=\"_blank\">University of Cambridge<\/a>, able to return any time to participate in the intellectual life of the college. <a class=\"dhtgD aw5Odc\" href=\"https:\/\/www.clarehall.cam.ac.uk\/news\/scienceandnature21\/\" target=\"_blank\">Clare Hall<\/a> is a graduate college devoted to research and scholarship and a culturally rich and intellectually exciting academic community. In 2018, he was elected to a Clare Hall Visiting Fellowship to advance his research and scholarship and mentor graduate students. He has held visiting posts in the Department of Medicine, the MRC Epidemiology Unit, and the MRC Biostatistics Unit of the University of Cambridge. He has been appointed a standing member of the NIH Biostatistical Methods and Research Design (BMRD) study section.<\/p>\n<p>He serves as a co-chair of the Genetics Task Force of the Environmental influences on Child Health Outcomes consortium (2023 \u2013 Present). He also serves on the Steering Committee of the newly-launched DEFINE-T2D (Definition, Etiology, Function: Integration to Enhance Type 2 Diabetes treatment) Consortium (2024 \u2013 Present), as a co-PI of a NIDDK-funded research project (U01DK140952).<\/p>\n<p><a href=\"https:\/\/cdn-dev.vanderbilt.edu\/t2-my-dev\/wp-content\/uploads\/sites\/1706\/2015\/01\/UChicago_Logo1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-527\" src=\"https:\/\/cdn-dev.vanderbilt.edu\/t2-my-dev\/wp-content\/uploads\/sites\/1706\/2015\/01\/UChicago_Logo1-244x300.jpg\" width=\"120\" height=\"148\" srcset=\"https:\/\/cdn-dev.vanderbilt.edu\/t2-my-dev\/wp-content\/uploads\/sites\/1706\/2015\/01\/UChicago_Logo1-244x300.jpg 244w, https:\/\/cdn-dev.vanderbilt.edu\/t2-my-dev\/wp-content\/uploads\/sites\/1706\/2015\/01\/UChicago_Logo1.jpg 325w\" sizes=\"auto, (max-width: 120px) 100vw, 120px\" \/><\/a>He has conducted research in genomics and translational science in the <a href=\"https:\/\/medicine.uchicago.edu\/sections\/genetic-medicine\/\" target=\"_blank\" rel=\"nofollow\">Section of Genetic Medicine<\/a> of the <a href=\"http:\/\/www.uchicago.edu\" target=\"_blank\" rel=\"nofollow\">University of Chicago<\/a> and the <a href=\"http:\/\/www.uva.nl\/en\/shared-content\/organisatiegids\/en\/university-of-amsterdam\/faculties\/faculty-of-medicine\/faculty-of-medicine.html\" rel=\"nofollow\">Faculty of Medicine<\/a> (AMC) of the University of Amsterdam. He was trained in Mathematics and Statistical Genetics.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>We develop and apply genomic and computational methods to investigate the genetic architecture of complex traits, including disease risk and drug response. We are interested in what can be learned from DNA sequence and multi-omics data about disease mechanism, therapeutic intervention, molecular evolution, and genome function. An ongoing project involves understanding gene regulation across tissues&#8230;<\/p>\n","protected":false},"author":3547,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"tags":[],"class_list":["post-3","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/my.dev.vanderbilt.edu\/ericgamazon\/wp-json\/wp\/v2\/pages\/3","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/my.dev.vanderbilt.edu\/ericgamazon\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/my.dev.vanderbilt.edu\/ericgamazon\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/ericgamazon\/wp-json\/wp\/v2\/users\/3547"}],"replies":[{"embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/ericgamazon\/wp-json\/wp\/v2\/comments?post=3"}],"version-history":[{"count":186,"href":"https:\/\/my.dev.vanderbilt.edu\/ericgamazon\/wp-json\/wp\/v2\/pages\/3\/revisions"}],"predecessor-version":[{"id":1292,"href":"https:\/\/my.dev.vanderbilt.edu\/ericgamazon\/wp-json\/wp\/v2\/pages\/3\/revisions\/1292"}],"wp:attachment":[{"href":"https:\/\/my.dev.vanderbilt.edu\/ericgamazon\/wp-json\/wp\/v2\/media?parent=3"}],"wp:term":[{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/my.dev.vanderbilt.edu\/ericgamazon\/wp-json\/wp\/v2\/tags?post=3"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}